ROXY EC for MS
Dedicated Electrochemistry system for EC/MS
- Single compound conversion (oxidation/reduction)
- Direct on-line EC/MS, without chromatography (LC)
- All parts supplied for immediate installation and use
- Fast metabolite profiling Phase 1 and 2 metabolism
- Huge time and cost savings
ROXY EC for MS


Details
The ROXY™ EC is the ideal introduction system for Electrospray Ionization (ESI)-MS for single compound conversion. For known compounds (e.g., drug candidates, pollutants, pesticides, etc) a quick profiling and/or reconfirmation of potential metabolites is often sufficient for decision making. Therefore, target compounds can be directly infused through the electrochemical ReactorCell™ into the MS, often without the need of any liquid chromatographic separation (HPLC), making EC/MS a very powerful tool for fast metabolic profiling and related applications.
The resulting time and cost savings are substantial when compared with daunting in vivo or in vitro experiments. The ROXY™ EC System is supplied with a dual syringe infusion pump and all connecting tubing and parts for immediate installation and use. A short movie is available demostrating setting up a ROXY measurement.
Downloads
Product Flyers
- ROXY EC System - Potentiostat incl Pump, Cell, Software
Application Notebook
- 210_050_01 - Application Notebook ROXY
Manuals
- 210_7001_01 - User instruction uPrepCell 2.0 High Pressure
- 210_7010_08 - ROXY Potentiostat user manual
- 210_7011_04 - ROXY EC Installation guide
- 210_7013_03 - ROXY EC guideline for SS reducing electrodes
- 210_7014_02 - ReactorCell user manual
- 210_7015_02 - Dialogue software installation and quick start
- 210_7016_02 - ROXY EC system Quick Start Up
- 210_7018_01 - Dialogue for ROXY handson training
- 210_7019_01 - ROXY EC system DEMO start up
- 210_7050_06 - ROXY EC system Installation Requirements
Posters
- 221_070_01 - Online EC MS A Powerful Tool for Fast Prediction of Phase I and II Drug Metabolism
- 221_076_01 - Expanding Role of Electrochemistry Mass Spectrometry in Life Sciences
- 221_077_01 - Novel method for efficient reduction of disulfide bonds in peptides and proteins prior MS detection
- 221_078_01 - Identification of electrochemically synthesized metabolites
- 221_079_01 - Insights into Nucleic Acids Oxidation by ElectrochemistryLiquid ChromatographyMass Spectrometry
- 221_090_01 - Degradation of Xenobiotics and Binding to Organic Matter by OnLine EC MS
- 221_105_01 - Controlled Reduction of Disulfide Bonds in Biopharmaceuticals Using an Electrochemical Reactor Cell online with LCMS Rolduc 2014
- 221_106_01 - ElectrochemistryMS a Powerful Tool in Drug Metabolism Rolduc 2014
- 221_107_01 - ElectrochemistryMS a Powerful Tool in Drug Metabolism ASMS 2014
- 221_108_01 - Controlled Reduction of Disulfide Bonds in Proteins and Peptides Using an Electrochemical Reactor Cell in online LCECMS ASMS 2014
- 221_115_01 - Controlled Reduction of Disulfide Bonds in Biopharmaceuticals ElCheMS2015
- 221_116_01 - Enhanced Pharmaceutical Stability ElCheMS2015
- 221_117_01 - Mimicking Drug Metabolism ElCheMS2015
- 221_118_01 - Electrochem Reduction of Disulfide Bonds ASMS2015
- 221_120_01 - ECHDX for the Analysis of Protein Therapeutics HOS2015
- 221_226_01 - The Application of ElectrochemistryMS to Pharmaceutical Stability Testing and Degradant Synthesis
Applications
ROXY Application Notes
The ROXY™ EC is the ideal introduction system for Electrospray Ionization (ESI)-MS for single compound conversion. For known compounds (e.g., drug candidates, pollutants, pesticides, etc) a quick profiling and/or reconfirmation of potential metabolites is often sufficient for decision making. Therefore, target compounds can be directly infused through the electrochemical ReactorCell™ into the MS, often without the need of any liquid chromatographic separation (HPLC), making EC/MS a very powerful tool for fast metabolic profiling and related applications.
The resulting time and cost savings are substantial when compared with daunting in vivo or in vitro experiments. The ROXY™ EC System is supplied with a dual syringe infusion pump and all connecting tubing and parts for immediate installation and use. A short movie is available demostrating setting up a ROXY measurement.
Product Flyers
- ROXY EC System - Potentiostat incl Pump, Cell, Software
Application Notebook
- 210_050_01 - Application Notebook ROXY
Manuals
- 210_7001_01 - User instruction uPrepCell 2.0 High Pressure
- 210_7010_08 - ROXY Potentiostat user manual
- 210_7011_04 - ROXY EC Installation guide
- 210_7013_03 - ROXY EC guideline for SS reducing electrodes
- 210_7014_02 - ReactorCell user manual
- 210_7015_02 - Dialogue software installation and quick start
- 210_7016_02 - ROXY EC system Quick Start Up
- 210_7018_01 - Dialogue for ROXY handson training
- 210_7019_01 - ROXY EC system DEMO start up
- 210_7050_06 - ROXY EC system Installation Requirements
Posters
- 221_070_01 - Online EC MS A Powerful Tool for Fast Prediction of Phase I and II Drug Metabolism
- 221_076_01 - Expanding Role of Electrochemistry Mass Spectrometry in Life Sciences
- 221_077_01 - Novel method for efficient reduction of disulfide bonds in peptides and proteins prior MS detection
- 221_078_01 - Identification of electrochemically synthesized metabolites
- 221_079_01 - Insights into Nucleic Acids Oxidation by ElectrochemistryLiquid ChromatographyMass Spectrometry
- 221_090_01 - Degradation of Xenobiotics and Binding to Organic Matter by OnLine EC MS
- 221_105_01 - Controlled Reduction of Disulfide Bonds in Biopharmaceuticals Using an Electrochemical Reactor Cell online with LCMS Rolduc 2014
- 221_106_01 - ElectrochemistryMS a Powerful Tool in Drug Metabolism Rolduc 2014
- 221_107_01 - ElectrochemistryMS a Powerful Tool in Drug Metabolism ASMS 2014
- 221_108_01 - Controlled Reduction of Disulfide Bonds in Proteins and Peptides Using an Electrochemical Reactor Cell in online LCECMS ASMS 2014
- 221_115_01 - Controlled Reduction of Disulfide Bonds in Biopharmaceuticals ElCheMS2015
- 221_116_01 - Enhanced Pharmaceutical Stability ElCheMS2015
- 221_117_01 - Mimicking Drug Metabolism ElCheMS2015
- 221_118_01 - Electrochem Reduction of Disulfide Bonds ASMS2015
- 221_120_01 - ECHDX for the Analysis of Protein Therapeutics HOS2015
- 221_226_01 - The Application of ElectrochemistryMS to Pharmaceutical Stability Testing and Degradant Synthesis