ROXY Reaction Systems
Mimicking nature’s redox reactions
- Fast synthesis of metabolites (µ-preparative)
- Rapid risk assessments of drug-protein binding
- Signal enhancement in MS
- Electrochemical cleavage of proteins/peptides
- Reduction of disulfide bonds
- Oxidative stress/damage of proteins, DNA, lipids, etc.
ROXY Reaction Systems


Details
The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the investigation of drug metabolism. It offers fast electrochemical synthesis of drug metabolites for reliable quantification by mass spectrometry (MS) to be operated as a high throughput screening system. The ROXY EC system and the ROXY EC/LC system provide all the tools for EC/MS research.
For further explanation see the video recording of the ASMS presentation of prof Uwe Karst (2010) and the tutorials on our website, such as a computer animation on YouTube made by University of Twente.
Downloads
ROXY Product Brochure
- ROXY - product brochure
ROXY manuals
- 204_0010A_02 - uPrepCell2.0 user manual
- 204_0010_05 - uPrepCell user manual
- 204_0016_01 - uPrepCell priming instruction
- 204_0017_01 - Instruction uPrepCell laminated electrodes
- 204_0018_02 - Guideline for metabolite synthesis
- 204_7000_03 - User instruction uPrepCell high pressure
- 204_7002_01 - Guidelines on the use of ReactorCell with activated Ti WE
- 206_0010_01 - SynthesisCell user manual
- 206_0014_01 - SynthesisCell startup guide
- 206_7000_01 - SB filling and storage
- 210_7001_01 - User instruction uPrepCell 2.0 High Pressure
- 210_7010_08 - ROXY Potentiostat user manual
- 210_7011_04 - ROXY EC Installation guide
- 210_7013_03 - ROXY EC guideline for SS reducing electrodes
- 210_7014_02 - ReactorCell user manual
- 210_7015_02 - Dialogue software installation and quick start
- 210_7016_02 - ROXY EC system Quick Start Up
- 210_7018_01 - Dialogue for ROXY handson training
- 210_7019_01 - ROXY EC system DEMO start up
- 210_7050_06 - ROXY EC system Installation Requirements
Applications
ROXY Application Notes
The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the investigation of drug metabolism. It offers fast electrochemical synthesis of drug metabolites for reliable quantification by mass spectrometry (MS) to be operated as a high throughput screening system. The ROXY EC system and the ROXY EC/LC system provide all the tools for EC/MS research.
For further explanation see the video recording of the ASMS presentation of prof Uwe Karst (2010) and the tutorials on our website, such as a computer animation on YouTube made by University of Twente.
ROXY Product Brochure
- ROXY - product brochure
ROXY manuals
- 204_0010A_02 - uPrepCell2.0 user manual
- 204_0010_05 - uPrepCell user manual
- 204_0016_01 - uPrepCell priming instruction
- 204_0017_01 - Instruction uPrepCell laminated electrodes
- 204_0018_02 - Guideline for metabolite synthesis
- 204_7000_03 - User instruction uPrepCell high pressure
- 204_7002_01 - Guidelines on the use of ReactorCell with activated Ti WE
- 206_0010_01 - SynthesisCell user manual
- 206_0014_01 - SynthesisCell startup guide
- 206_7000_01 - SB filling and storage
- 210_7001_01 - User instruction uPrepCell 2.0 High Pressure
- 210_7010_08 - ROXY Potentiostat user manual
- 210_7011_04 - ROXY EC Installation guide
- 210_7013_03 - ROXY EC guideline for SS reducing electrodes
- 210_7014_02 - ReactorCell user manual
- 210_7015_02 - Dialogue software installation and quick start
- 210_7016_02 - ROXY EC system Quick Start Up
- 210_7018_01 - Dialogue for ROXY handson training
- 210_7019_01 - ROXY EC system DEMO start up
- 210_7050_06 - ROXY EC system Installation Requirements