ROXY Reaction Systems

Mimicking nature’s redox reactions

 

  • Fast synthesis of metabolites (µ-preparative)
  • Rapid risk assessments of drug-protein binding
  • Signal enhancement in MS
  • Electrochemical cleavage of proteins/peptides
  • Reduction of disulfide bonds
  • Oxidative stress/damage of proteins, DNA, lipids, etc.

ROXY Reaction Systems

Details

The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the investigation of drug metabolism. It offers fast electrochemical synthesis of drug metabolites for reliable quantification by mass spectrometry (MS) to be operated as a high throughput screening system. The ROXY EC system and the ROXY EC/LC system provide all the tools for EC/MS research.


For further explanation see the video recording of the ASMS presentation of prof Uwe Karst (2010) and the tutorials on our website, such as a computer animation on YouTube made by University of Twente. 

Downloads

ROXY Product Brochure

ROXY manuals

Applications

ROXY Application Notes

The on-line coupling of Electrochemistry (EC) with LC/MS has shown great potential for the investigation of drug metabolism. It offers fast electrochemical synthesis of drug metabolites for reliable quantification by mass spectrometry (MS) to be operated as a high throughput screening system. The ROXY EC system and the ROXY EC/LC system provide all the tools for EC/MS research.


For further explanation see the video recording of the ASMS presentation of prof Uwe Karst (2010) and the tutorials on our website, such as a computer animation on YouTube made by University of Twente. 

ROXY Product Brochure

ROXY manuals

ROXY Application Notes

Product Images